Altered colonic mucosal availability of n-3 and n-6 polyunsaturated fatty acids in ulcerative colitis and the relationship to disease activity
Daniel Pearl, Mojgan Masoodi, Michael Eiden, Janine Brümmer, Darren R. Gullick, Tricia M. McKeever +7 more
Journal of Crohn s and Colitis
Abstract
Higher AA, AA:EPA ratio, DPA and DHA and lower LA, α-LNA and EPA are seen in inflamed mucosa in UC and correlate with severity of inflammation. This suggests an alteration in fatty acid metabolism in the inflamed gut mucosa, which may offer novel targets for intervention and should be considered if nutritional strategies are used.
Extracted Claims
7 claims extracted from this paper into the knowledge graph
EPA (Eicosapentaenoic Acid) is lower in inflamed mucosa in UC
“Higher AA, AA:EPA ratio, DPA and DHA and lower LA, α-LNA and EPA are seen in inflamed mucosa in UC and correlate with severity of inflammation.”
DPA (Docosapentaenoic Acid) is higher in inflamed mucosa in UC
“Higher AA, AA:EPA ratio, DPA and DHA and lower LA, α-LNA and EPA are seen in inflamed mucosa in UC and correlate with severity of inflammation.”
AA:EPA ratio is higher in inflamed mucosa in UC
“Higher AA, AA:EPA ratio, DPA and DHA and lower LA, α-LNA and EPA are seen in inflamed mucosa in UC and correlate with severity of inflammation.”